Pregabalin and Nortriptyline Tablets

Pregabalin and Nortriptyline Tablets come with the branding “Nucalm-NT” and are a combination medication used for the treatment of neuropathic pain such as peripheral neuropathy due to diabetes, after shingles, and nerve pain following spinal cord injury. Neuropathic pain is a type of continuous, chronic pain resulting from a dysfunction in the normal functioning of the nervous system or nerve injury.

Pregabalin and Nortriptyline Tablets consist of Pregabalin, an anticonvulsant acting on the neurotransmitters in the brain involved in transmitting pain signals and Nortriptyline which is an antidepressant that enhances serotonin and noradrenaline in the ECF decreasing the pain signals. Together, they assist in resolving neuropathic pain.

Medical Benefits

• It is used to treat neuropathic pain which is caused by conditions such as diabetic peripheral neuropathy, postherpetic neuralgia and spinal cord injury neuropathic pain.
• Pregabalin, like other anticonvulsants, works on the neurochemicals involved in transmitting pain signals across the nervous system.
• Nortriptyline is an anti-depressant drug that will increase nerve transmitters in the brain such as serotonin and noradrenaline, thus minimizing pain signals.
• Both of them assist in the management of neuropathic pain associated with nerve injury.

Directions For Use

• Swallow Pregabalin and Nortriptyline Tablets exactly as your doctor advised it to be used.
• It should be ingested together with meals to avoid any abnormalities in the stomach.
• Consume it with water and avoid chewing or crushing.
• Ensure the medication is out of reach of children and pets.

Storage

• Do not keep the tablet in direct daylight.
• Locate it in a dry cool place.
• Make sure that the lid is on properly to retain the components of the ingredients.
• Store Pregabalin and Nortriptyline Tablets away from children’s and pets’ reach.

Precautions

• Consult a doctor before its intake as it may interact with antidepressants (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline, citalopram, escitalopram, bupropion), muscle relaxants (cyclobenzaprine), antiemetic (ondansetron).
• This medicine might cause increased drowsiness and sleepiness. So consult a doctor before taking this medicine.
• Inform your doctor if you have angioedema, creatine kinase elevations, heart problems, depression, fits, glaucoma, schizophrenia, bipolar disorder, thyroid problems, urinary retention, kidney and liver problems.
• Avoid consumption of alcohol while taking this medicine as it may cause increased drowsiness and sleepiness.
• It may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

Side Effects

• Blurred vision
• Peripheral oedema (swelling of lower legs and hands)
• Weight gain
• Sleepiness
• Nausea
• Dizziness
• Dry mouth

Frequently Asked Questions (FAQs)

Can I stop taking this medication if I feel well?

To treat your condition effectually, continue taking it for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking this medicine.

Is this tablet used to treat diabetic neuropathy

It is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Does this composition cause oedema?

It may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Does this medicine cause weight gain?

This tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.